徐元

个人基本简介

职称：副教授

学位：博士

毕业院校：南洋理工大学

电子邮件：xuyuan@sdau.edu.cn

徐元，主要从事糖类化合物的合成与应用，长期专注于抗菌化合物的设计、合成与性能评估，包括糖基抗菌聚合物、肽聚糖基免疫制剂等，同时也从事糖类化合物合成方法学开发研究。在CCS Chem., Biomacromolecules, J. Org. Chem. Polym. Chem.等期刊发表SCI论文20余篇。

主要经历

学科方向

糖化学与糖生物学、新型抗菌类糖药物设计与合成、糖与多肽固相合成

荣誉获奖

主要兼职

科研项目

代表文章

1. Yuan Xu, Shihao Song, Hongwei Duan, Yinyue Deng and Xue–Wei Liu, Combatting Pathogenic Bacteria with Synthetic Immunotherapeutics from Chitosan: Antibody Recruiting at Engineered Bacterial Surface with Peptidoglycan Analogs, CCS Chemistry 2024,6, 1448;

2. Yuan Xu, Hongbin Zhang and Xue-Wei Liu, Antimicrobial Carbohydrate-Based Macromolecules: Their Structures and Activities, J. Org. Chem. 2020, 85, 15827;

3. Yuan Xu, Xin Ge, Yuhan Zhang, Hongbin Zhang and Xue-Wei Liu, A mild one-pot synthesis to 2-iminothiazolines from thioureas and 1-bromo-1-nitroalkenes, RSC Adv. 2021, 11, 2221;

4. Yuan Xu and Xue-Wei Liu, The versatility of carbohydrates in antimicrobial applications, J. Chin. Chem. Soc., 2020, 67, 2204;

5. Yuan Xu, Kaixi Zhang, Sheethal Reghu, Yichao Lin, Mary B. Chan-Park and Xuewei Liu, Synthesis of antibacterial glycosylated polycaprolactones bearing imidazoliums with reduced hemolytic activity, Biomacromolecules, 2019, 20, 949;

6. Asadulla Mallick,^† Yuan Xu,^† Yichao Lin, Jingxi He, Mary B. Chan-Park and Xuewei Liu, Oxadiazabicyclooctenone as a versatile monomer for the construction of pH sensitive functional polymers via ROMP, Polym. Chem. 2018, 9, 372; (†co-first)

7. Qiao Sun, Shao-Peng Wang, Yuan Xu, Aihua Yin, Liu Yang, Jingheng Zhu, Chun-Ling Zheng, Guowei Wang, Zheng Fang, Shanhong Sui, Daixi Wang, Yan Dong, Dongshun Zhang, Chang-Sheng Wang and Kai Guo, Visible-Light-Induced Energy-Transfer-Mediated Hydrofunctionalization and Difunctionalization of Unsaturated Compounds via Sigma-Bond Homolysis of Energy-Transfer Acceptors. ACS Catalysis 2025, 15, 1854-1941.

8. Aoxin Guo, Yuan Xu, Zhen-Hua Jia, Teck-Peng Loh and Xue-Wei Liu, Unraveling chemical glycosylation: DFT insights into factors imparting stereoselectivity, Green Synth. Catal. 2024, doi: 10.1016/j.gresc.2024.03.004;

9. Qiao Sun, Yuan Xu, Liu Yang, Chun-Ling Zheng, Guowei Wang, Hai-Bo Wang, Zheng Fang, Chang-Sheng Wang, and Kai Guo, Direct C–H Sulfuration: Synthesis of Disulfides, Dithiocarbamates, Xanthates, Thiocarbamates and Thiocarbonates, Chem. Asian. J. 2024, 19, e202400124;

10. Chang-Sheng Wang, Yuan Xu, Shao-Peng Wang, Chun-Ling Zheng, Guowei Wang and Qiao Sun, Recent Advances in Selective C–H Mono-/Dichalcogenation and Exclusive C–H Dichalcogenation of C(sp²)- and C(sp³)–H bonds, Org. Biomol. Chem. 2024, 22, 645;

11. Chang-Sheng Wang, Yuan Xu, Yi-Liang Zhou, Chun-Ling Zheng, Guowei Wang and Qiao Sun, Recent Advances in the Dichalcogenation Reactions of Unsaturated Compounds Via Double Functionalization, Org. Chem. Front. 2023, 10, 4972;